Immunodiagnosis of active tuberculosis
نویسندگان
چکیده
منابع مشابه
Immunodiagnosis of tuberculosis: state of the art.
Undiagnosed and mismanaged tuberculosis (TB) continues to fuel the global TB epidemic. Rapid, accurate and early diagnosis of TB is therefore a priority to improve TB case detection and interrupt transmission. Although considerable improvements have been made in TB diagnostics, there are two major gaps in the existing diagnostics pipeline: (1) lack of a simple accurate point-of-care test that c...
متن کاملIdentification of early secretory antigen target-6 epitopes for the immunodiagnosis of active tuberculosis.
The early secretory antigenic target (ESAT)-6 purified protein and peptides from Mycobacterium tuberculosis were evaluated as antigens for the immunodiagnosis of tuberculosis (TB). Because the control of TB requires improved diagnostic procedures, efforts have increased to identify Mycobacterium tuberculosis-specific epitopes for the immunodiagnosis of active TB and to discriminate between acti...
متن کاملTuberculosis immunodiagnosis: delving below the surface.
It is one hundred and thirty years since Franz Ziehl and Friedrich Neelsen developed the rapid stain for acid-fast bacilli; 2 accurate point-of-care diagnosis of active tuberculosis (TB) remains a major unmet clinical need. With the sensitivity of the Ziehl–Neelsen stain in sputum less than 50% and more than 20% of TB cases negative on both acid-fast stain and culture for Mycobacterium tubercul...
متن کاملImmunodiagnosis of tuberculosis: a dynamic view of biomarker discovery.
Infection with Mycobacterium tuberculosis causes a variety of clinical conditions ranging from life-long asymptomatic infection to overt disease with increasingly severe tissue damage and a heavy bacillary burden. Immune biomarkers should follow the evolution of infection and disease because the host immune response is at the core of protection against disease and tissue damage in M. tuberculos...
متن کاملProceedings of Immunodiagnosis of Tuberculosis: New Questions, New Tools
Introduction: The first international meeting on new biomarkers and tools for the immunodiagnosis of M. tuberculosis infection and disease, entitled objective of the conference was to integrate the most recent knowledge generated through basic, translational, and clinical research that could lead to novel, improved immunodiagnostic tools for tuberculosis (TB). About 150 researchers from academi...
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ژورنال
عنوان ژورنال: Expert Review of Respiratory Medicine
سال: 2019
ISSN: 1747-6348,1747-6356
DOI: 10.1080/17476348.2019.1615888